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Solution: Inconsistent Particle Size of Active Pharmaceutical Ingredients (API) and Excipients?


Air Jet Sieve is employed across various industries to efficiently and accurately separate and classify powders and granular materials based on particle size. Below is an application case of an air jet sieve:


In the pharmaceutical industry, air jet sieves are commonly used to ensure the quality and consistency of drug formulations. For instance, in tablet production, careful control of the particle size of the active pharmaceutical ingredient (API) and other excipients is necessary to ensure proper tablet compression and dissolution characteristics. 


One application case involves XXX Pharmaceutical Company, which encountered issues in tablet compression and the dissolution properties of specific drug formulations. Analysis revealed inconsistent particle sizes between the active pharmaceutical ingredients and excipients, resulting in inconsistent tablet quality.


To address this issue, XXX Pharma utilized Air Jet Sieve AS-200 Pro to precisely control the particle size distribution of both API and excipients. The air jet sieve enables manufacturers to rapidly and accurately separate particles based on their size, ensuring that only particles within the desired size range are used in tablet formulations.

As a result, the compression and dissolution properties of the tablets significantly improved, enhancing product quality and reducing batch wastage. Additionally, the use of the AS-200 Pro not only reduced waste but also increased production efficiency.

This case illustrates the importance of particle size control in pharmaceutical manufacturing and the irreplaceable role of efficient air jet sieves in consistently ensuring the production of high-quality drug formulations.


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